Multistep mechanism of G-quadruplex resolution during DNA replication-Reference-Cited by-同舟云学术

Multistep mechanism of G-quadruplex resolution during DNA replication

Published:2021-09-24 Issue:39 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Sato Koichi¹^ORCID,Martin-Pintado Nerea¹,Post Harm²,Altelaar Maarten²^ORCID,Knipscheer Puck¹^ORCID

Affiliation:

1. Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, Uppsalalaan 8, Utrecht 3584 CT, Netherlands.

2. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, Netherlands.

Abstract

DNA helicases DHX36 and FANCJ constitute a previously unknown pathway that resolves G-quadruplex structures during DNA replication.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference79 articles.

1. HELIX FORMATION BY GUANYLIC ACID

2. Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

3. Quadruplex DNA: sequence, topology and structure

4. Prevalence of quadruplexes in the human genome

5. Epigenetic Instability due to Defective Replication of Structured DNA

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