A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins-Reference-Cited by-同舟云学术

A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins

Published:2020-06-05 Issue:23 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Gerstmans H.¹²³^ORCID,Grimon D.¹,Gutiérrez D.¹⁴,Lood C.²⁵^ORCID,Rodríguez A.⁴,van Noort V.⁵⁶^ORCID,Lammertyn J.³^ORCID,Lavigne R.²,Briers Y.¹^ORCID

Affiliation:

1. Department of Biotechnology, Ghent University, Valentin Vaerwyckweg 1, 9000 Gent, Belgium.

2. Department of Biosystems, KU Leuven, Kasteelpark Arenberg 21, 3001 Leuven, Belgium.

3. Department of Biosystems, KU Leuven, Willem de Croylaan 42, 3001 Leuven, Belgium.

4. Dairy Research Institute of Asturias, Spanish National Research Council (IPLA-CSIC), Paseo Río Linares, s/n, 33300 Villaviciosa, Asturias, Spain.

5. Department of Microbial and Molecular Systems, KU Leuven, Kasteelpark Arenberg 23, 3001 Leuven, Belgium.

6. Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 Leiden, Netherlands.

Abstract

We have developed a novel platform for engineered lysins to fill the preclinical pipeline of antimicrobials.

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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