The fibrinolytic system enables the onset of Plasmodium infection in the mosquito vector and the mammalian host-Reference-Cited by-同舟云学术

The fibrinolytic system enables the onset of Plasmodium infection in the mosquito vector and the mammalian host

Published:2021-02-05 Issue:6 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Alves e Silva Thiago Luiz¹²^ORCID,Radtke Andrea³^ORCID,Balaban Amanda¹,Pascini Tales Vicari⁴^ORCID,Pala Zarna Rajeshkumar⁴,Roth Alison⁵^ORCID,Alvarenga Patricia H.¹²,Jeong Yeong Je⁴,Olivas Janet⁴,Ghosh Anil K.¹,Bui Hanhvy¹^ORCID,Pybus Brandon S.⁵^ORCID,Sinnis Photini¹^ORCID,Jacobs-Lorena Marcelo¹^ORCID,Vega-Rodríguez Joel¹^ORCID

Affiliation:

1. The W. Harry Feinstone Department of Molecular Microbiology and Immunology and Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

2. Laboratório de Bioquímica de Resposta ao Estresse, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.

3. Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.

4. Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

5. Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.

Abstract

Plasmodium uses the fibrinolytic system to overcome physical barriers in the mosquito and vertebrate host.

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference78 articles.

1. The development of malaria parasites in the mosquito midgut