Lewis acid–catalyzed domino generation/[2,3]-sigmatropic rearrangement of ammonium ylides to access chiral azabicycles-Reference-Cited by-同舟云学术

Lewis acid–catalyzed domino generation/[2,3]-sigmatropic rearrangement of ammonium ylides to access chiral azabicycles

Published:2021-01-29 Issue:5 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Xi Song¹^ORCID,Dong Jiawei¹^ORCID,Chen Haohua²^ORCID,Dong Qiuyan¹,Yang Jiao¹,Tan Qiuyuan¹,Zhang Changhui¹,Lan Yu²³^ORCID,Zhang Min¹²⁴^ORCID

Affiliation:

1. Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing, China.

2. Chongqing Key Laboratory of Theoretical and Computational Chemistry, School of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China.

3. Green Catalysis Center, College of Chemistry, Zhengzhou University, Zhengzhou, China.

4. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.

Abstract

A domino process to prepare chiral azabicycles with bridgehead quaternary stereogenic centers is reported.

Funder

National Natural Science Foundation of China

Chongqing Science and Technology Commission, Chongqing People’s Municipal Government

State Key Laboratory of Phytochemistry and Plant Resources in West China

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference59 articles.

1. Asymmetric Ylide Reactions: Epoxidation, Cyclopropanation, Aziridination, Olefination, and Rearrangement