How can same-gene mutations promote both cancer and developmental disorders?-Reference-Cited by-同舟云学术

How can same-gene mutations promote both cancer and developmental disorders?

Published:2022-01-14 Issue:2 Volume:8 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Nussinov Ruth¹²^ORCID,Tsai Chung-Jung¹,Jang Hyunbum¹^ORCID

Affiliation:

1. Computational Structural Biology Section, Frederick National Laboratory for Cancer Research in the Laboratory of Cancer Immunometabolism, National Cancer Institute, Frederick, MD 21702, USA.

2. Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

Abstract

This review offers why same-gene mutations can lead to cancer and neurodevelopmental disorders and why a high risk of cancer.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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