Altered d -glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRI-Reference-Cited by-同舟云学术

Altered d -glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRI

Published:2020-05-15 Issue:20 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Huang Jianpan¹^ORCID,van Zijl Peter C. M.²³,Han Xiongqi¹^ORCID,Dong Celia M.⁴,Cheng Gerald W. Y.⁵^ORCID,Tse Kai-Hei⁵^ORCID,Knutsson Linda²⁶^ORCID,Chen Lin²³^ORCID,Lai Joseph H. C.¹^ORCID,Wu Ed X.⁴^ORCID,Xu Jiadi²³^ORCID,Chan Kannie W. Y.¹²⁷^ORCID

Affiliation:

1. Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.

2. Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

3. F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD, USA.

4. Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, China.

5. Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.

6. Department of Medical Radiation Physics, Lund University, Lund, Sweden.

7. City University of Hong Kong Shenzhen Research Institute, Shenzhen, China.

Abstract

d -glucose–enhanced MRI detects altered CSF flow and glucose utilization in early Alzheimer’s disease when plaque formation begins.

Funder

National Institutes of Health

City University of Hong Kong

Swedish Cancer Foundation

Research Grants Council, University Grants Committee, Hong Kong

Swedish Research Council Formas

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

1. Alzheimer Mechanisms and Therapeutic Strategies

2. Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

3. Alterations in Cerebral Blood Flow and Glucose Utilization in Mice Overexpressing the Amyloid Precursor Protein

4. Behavioral Changes and Hippocampus Glucose Metabolism in APP/PS1 Transgenic Mice via Electro-acupuncture at Governor Vessel Acupoints

5. Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease

Cited by 65 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Glucose uptake in pigment glia suppresses tau-induced inflammation and photoreceptor degeneration inDrosophila;2024-08-19

2. CEST effect of dimethyl sulfoxide at negative offset frequency;NMR in Biomedicine;2024-08-12

3. Attention-Based MultiOffset Deep Learning Reconstruction of Chemical Exchange Saturation Transfer (AMO-CEST) MRI;IEEE Journal of Biomedical and Health Informatics;2024-08

4. Editorial: Visualization and assessment of cerebral vasculature, cerebrospinal fluids, and the brain parenchyma in dementia and aging;Frontiers in Aging Neuroscience;2024-06-18

5. Exploring neurodegenerative disorders using advanced magnetic resonance imaging of the glymphatic system;Frontiers in Psychiatry;2024-04-08