Enhanced therapeutic index of an antimicrobial peptide in mice by increasing safety and activity against multidrug-resistant bacteria-Reference-Cited by-同舟云学术

Enhanced therapeutic index of an antimicrobial peptide in mice by increasing safety and activity against multidrug-resistant bacteria

Published:2020-05 Issue:18 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Di Y. P.¹^ORCID,Lin Q.¹^ORCID,Chen C.¹^ORCID,Montelaro R. C.²^ORCID,Doi Y.³⁴^ORCID,Deslouches B.¹^ORCID

Affiliation:

1. Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.

2. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

3. Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

4. Departments of Microbiology and Infectious Diseases, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.

Abstract

Enantiomeric optimization markedly increased safety and efficacy of a cationic peptide against multidrug-resistant pathogens.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

1. Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens

2. Nano-therapeutics: A revolution in infection control in post antibiotic era

3. Economic burden of antibiotic resistance in ESKAPE organisms: a systematic review

4. The effects of antimicrobial peptide Nal-P-113 on inhibiting periodontal pathogens and improving periodontal status;Wang H.;Biomed. Res. Int.,2018

5. Dermatologic toxicity from novel therapy using antimicrobial peptide LL-37 in melanoma: A detailed examination of the clinicopathologic features

Cited by 90 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel multidomain peptide self-assembly biomaterials based on bola structure and terminal anchoring: Nanotechnology meets antimicrobial therapy;Materials Today Bio;2024-10

2. Lung antimicrobial proteins and peptides: from host defense to therapeutic strategies;Physiological Reviews;2024-10-01

3. Antibacterial oxygen-sulfur terminal polymers from a facile initiator-strategy;Chemical Engineering Journal;2024-07

4. Metal-based nanomaterials with enzyme-like characteristics for bacterial rapid detection and control;Coordination Chemistry Reviews;2024-07

5. Rational design of a new short anticancer peptide with good potential for cancer treatment;European Journal of Medicinal Chemistry;2024-07