Immunity drives TET1 regulation in cancer through NF-κB-Reference-Cited by-同舟云学术

Immunity drives TET1 regulation in cancer through NF-κB

Published:2018-06 Issue:6 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Collignon Evelyne¹^ORCID,Canale Annalisa²,Al Wardi Clémence¹^ORCID,Bizet Martin¹,Calonne Emilie¹^ORCID,Dedeurwaerder Sarah¹,Garaud Soizic³,Naveaux Céline³,Barham Whitney⁴,Wilson Andrew⁴,Bouchat Sophie⁵,Hubert Pascale⁶^ORCID,Van Lint Carine⁵,Yull Fiona⁴,Sotiriou Christos⁷,Willard-Gallo Karen³^ORCID,Noel Agnès²,Fuks François¹

Affiliation:

1. Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB (Université libre de Bruxelles)–Cancer Research Center (U-CRC), ULB, Brussels, Belgium.

2. Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA)–Cancer, University of Liège, Liège, Belgium.

3. Molecular Immunology Unit, Institut Jules Bordet, ULB, Brussels, Belgium.

4. Department of Cancer Biology, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.

5. Service of Molecular Virology, Department of Molecular Biology, U-CRC, ULB, Gosselies, Belgium.

6. Laboratory of Experimental Pathology, GIGA-Cancer, University of Liège, Liège, Belgium.

7. Breast Cancer Translational Research Laboratory, Jules Bordet Institute, ULB, Brussels, Belgium.

Abstract

A new paradigm has emerged showing that the immune system can influence cancer cell epigenetics through NF-κB–mediated regulation of TET1.

Funder

Fonds De La Recherche Scientifique - FNRS

Fédération Wallonie-Bruxelles

Fondation contre le Cancer

Action de Recherche Concertée

Fondation Leon Fredericq

Centre anticancéreux

l’Oreal Foundation

Interuniversity Attraction Poles

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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