Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair-Reference-Cited by-同舟云学术

Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

Published:2019-08-02 Issue:8 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Herberg S.¹^ORCID,McDermott A. M.²³^ORCID,Dang P. N.¹,Alt D. S.¹^ORCID,Tang R.¹^ORCID,Dawahare J. H.³,Varghai D.¹,Shin J.-Y.¹,McMillan A.¹,Dikina A. D.¹,He F.¹^ORCID,Lee Y. B.¹,Cheng Y.¹,Umemori K.¹,Wong P. C.⁴^ORCID,Park H.¹,Boerckel J. D.²³⁵^ORCID,Alsberg E.¹⁶⁷^ORCID

Affiliation:

1. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.

2. Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania,

3. Philadelphia, PA, USA.

4. Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, USA.

5. School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.

6. Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.

7. Department of Orthopaedic Surgery, Case Western Reserve University, Cleveland, OH, USA.

Abstract

Mesenchymal condensations promote defect repair by mimicking cellular, morphogenetic, and mechanical aspects of bone development.

Funder

National Heart, Lung, and Blood Institute

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Dental and Craniofacial Research

Indiana Clinical and Translational Sciences Institute

Naughton Foundation

Ohio Biomedical Research Commercialization Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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