The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks-Reference-Cited by-同舟云学术

The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks

Published:2020-04-10 Issue:15 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Jiménez-Martín Alberto¹^ORCID,Saugar Irene¹^ORCID,Joseph Chinnu Rose²^ORCID,Mayer Alexandra²^ORCID,Lehmann Carl P.¹,Szakal Barnabas²^ORCID,Branzei Dana²³^ORCID,Tercero José Antonio¹^ORCID

Affiliation:

1. Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain.

2. IFOM, The FIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy.

3. Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (IGM-CNR), Via Abbiategrasso 207, 27100 Pavia, Italy.

Abstract

Mgs1 contributes to genome stability by helping to avoid unwanted recombination at sites of perturbed DNA replication.

Funder

European Research Council

Italian Association for Cancer Research

Spanish Ministry of Science, Innovation and Universities

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Causes of Genome Instability

2. DNA damage tolerance

3. Tolerating DNA damage during eukaryotic chromosome replication

4. Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

5. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO

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