Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications-Reference-Cited by-同舟云学术

Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications

Published:2021-11-19 Issue:47 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Bhalla Sherry¹^ORCID,Melnekoff David T.²^ORCID,Aleman Adolfo¹³^ORCID,Leshchenko Violetta¹³^ORCID,Restrepo Paula¹³^ORCID,Keats Jonathan⁴^ORCID,Onel Kenan²³³⁵⁶,Sawyer Jeffrey R.⁷^ORCID,Madduri Deepu¹³,Richter Joshua¹³^ORCID,Richard Shambavi¹³^ORCID,Chari Ajai¹³,Cho Hearn Jay¹³^ORCID,Dudley Joel T.⁸^ORCID,Jagannath Sundar¹³,Laganà Alessandro¹²⁹^ORCID,Parekh Samir¹³⁹^ORCID

Affiliation:

1. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

2. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

3. Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

4. Translational Genomics Research Institute, Phoenix, AZ, USA.

5. Department of Pediatric Hematology and Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

6. Department of Pathology, Molecular, and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

7. Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

8. Tempus Labs Inc., Chicago, IL, USA.

9. Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Abstract

Integrative multiomics analysis of myeloma identifies 12 disease subtypes defined by specific patterns of genetic alterations.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference79 articles.

1. Multiple myeloma

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5. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

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