De-scattering with Excitation Patterning enables rapid wide-field imaging through scattering media

Author:

Zheng Cheng12,Park Jong Kang234ORCID,Yildirim Murat25ORCID,Boivin Josiah R.5ORCID,Xue Yi126ORCID,Sur Mriganka5ORCID,So Peter T. C.123ORCID,Wadduwage Dushan N.237ORCID

Affiliation:

1. Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.

2. Laser Biomedical Research Center, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.

3. Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.

4. ASML, Wilton, CT 06897, USA.

5. Picower Institute for Learning and Memory, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.

6. Deptartment of Electrical Engineering and Computer Sciences, University of California, Berkeley, 558 Cory Hall, Berkeley, CA, 94720, USA.

7. Center for Advanced Imaging, Faculty of Arts and Sciences, Harvard University, Cambridge, MA 02138, USA.

Abstract

Computational imaging in combination with full-field multiphoton microscopy demonstrates rapid in vivo deep tissue imaging.

Funder

National Institutes of Health

Samsung Advanced Institute of Technology

Hamamatsu Corporation

Singapore–Massachusetts Institute of Technology Alliance for Research and Technology (SMART) Center

BioSystems and Micromechanics

Center for Advanced Imaging at Harvard University

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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