Cryo-EM structure of the calcium homeostasis modulator 1 channel-Reference-Cited by-同舟云学术

Cryo-EM structure of the calcium homeostasis modulator 1 channel

Author:

Ren Yue¹^ORCID,Wen Tianlei²,Xi Zhiqin²,Li Shunjin²,Lu Jing¹^ORCID,Zhang Xing³⁴^ORCID,Yang Xue¹^ORCID,Shen Yuequan¹²⁵^ORCID

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China.

2. College of Life Sciences, Nankai University, Tianjin 300071, China.

3. Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

4. Center of Cryo Electron Microscopy, Zhejiang University School of Medicine, Hangzhou, China.

5. Synergetic Innovation Center of Chemical Science and Engineering, Tianjin 300071, China.

Abstract

The cryo-EM structure of the CALHM1 channel reveals an octameric assembly and nearly the entire N terminus inside the pore.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China Stem Cell and Translational Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference27 articles.

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