A microneedle platform for buccal macromolecule delivery-Reference-Cited by-同舟云学术

A microneedle platform for buccal macromolecule delivery

Published:2021-01-22 Issue:4 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Caffarel-Salvador Ester¹²^ORCID,Kim Soyoung²^ORCID,Soares Vance²^ORCID,Tian Ryan Yu²,Stern Sarah R.²^ORCID,Minahan Daniel²^ORCID,Yona Raissa²^ORCID,Lu Xiaoya²,Zakaria Fauziah R.²^ORCID,Collins Joy²³^ORCID,Wainer Jacob²,Wong Jessica²,McManus Rebecca²^ORCID,Tamang Siddartha²,McDonnell Shane²,Ishida Keiko²^ORCID,Hayward Alison²³⁴^ORCID,Liu Xiewen²⁵,Hubálek František⁶^ORCID,Fels Johannes⁶^ORCID,Vegge Andreas⁶,Frederiksen Morten Revsgaard⁶^ORCID,Rahbek Ulrik⁶^ORCID,Yoshitake Tadayuki⁷,Fujimoto James⁷^ORCID,Roxhed Niclas²⁸^ORCID,Langer Robert¹²⁹^ORCID,Traverso Giovanni²³⁹^ORCID

Affiliation:

1. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Division of Gastroenterology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

4. Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

5. Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH, UK.

6. Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark.

7. Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

8. School of Electrical Engineering and Computer Science, Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden.

9. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

Microneedles with high drug-loaded tips allow fast and painless delivery of biologics into the buccal mucosa.

Funder

National Institutes of Health

Novo Nordisk

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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