The optoretinogram reveals the primary steps of phototransduction in the living human eye-Reference-Cited by-同舟云学术

The optoretinogram reveals the primary steps of phototransduction in the living human eye

Published:2020-09-11 Issue:37 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Pandiyan Vimal Prabhu¹^ORCID,Maloney-Bertelli Aiden¹^ORCID,Kuchenbecker James A.¹^ORCID,Boyle Kevin C.²³^ORCID,Ling Tong²⁴^ORCID,Chen Zhijie Charles²³^ORCID,Park B. Hyle⁵^ORCID,Roorda Austin⁶^ORCID,Palanker Daniel²⁴^ORCID,Sabesan Ramkumar¹^ORCID

Affiliation:

1. Department of Ophthalmology, University of Washington, Seattle, WA 98109, USA.

2. Hansen Experimental Physics Laboratory, Stanford, CA 94305, USA.

3. Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.

4. Department of Ophthalmology, Stanford University, Stanford, CA 94305, USA.

5. Department of Bioengineering, University of California, Riverside, CA 92521, USA.

6. School of Optometry, University of California, Berkeley, CA 94720, USA.

Abstract

Human cone photoreceptors undergo rapid nanometer-scale mechanical deformations during the first step of phototransduction.

Funder

National Eye Institute

Burroughs Wellcome Fund

MJ Murdock Charitable Trust

Foundation Fighting Blindness

Research to Prevent Blindness

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference53 articles.

1. G Proteins and Phototransduction

2. Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice

3. Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy

4. Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

5. In vivo optical imaging of physiological responses to photostimulation in human photoreceptors

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