Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease

Author:

Benhadou Farida12ORCID,Glitzner Elisabeth3ORCID,Brisebarre Audrey1,Swedlund Benjamin1ORCID,Song Yura1ORCID,Dubois Christine1,Rozzi Milena1,Paulissen Catherine1,del Marmol Veronique2ORCID,Sibilia Maria3ORCID,Blanpain Cédric14ORCID

Affiliation:

1. Laboratory of Stem Cells and Cancer, Université Libre de Bruxelles, Brussels, Belgium.

2. Dermatology Department, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.

3. Institute of Cancer Research, Department of Medicine I, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria.

4. WELBIO, Université Libre de Bruxelles, Brussels B-1070, Belgium.

Abstract

Vefga induces psoriasis by acting on keratinocytes through Flt1 and Nrp1 receptors.

Funder

European Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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