A novel cardiomyogenic role for Isl1 + neural crest cells in the inflow tract-Reference-Cited by-同舟云学术

A novel cardiomyogenic role for Isl1 + neural crest cells in the inflow tract

Published:2020-12-04 Issue:49 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Hatzistergos Konstantinos E.¹²³^ORCID,Durante Michael A.²⁴⁵^ORCID,Valasaki Krystalenia²,Wanschel Amarylis C. B. A.²^ORCID,Harbour J. William²⁴⁵^ORCID,Hare Joshua M.²⁵⁶

Affiliation:

1. Aristotle University of Thessaloniki, Faculty of Sciences, School of Biology, Department of Genetics, Development and Molecular Biology, Thessaloniki 54124, Greece.

2. Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

3. Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

4. Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

5. Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

6. Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Abstract

Cells previously thought to mainly form nerves in the heart turn out to be very important in cardiac muscle formation.

Funder

National Institutes of Health

Starr Foundation

Soffer Family Foundation

University of Miami Medical Scientist Training Program

Sheila and David Fuente Graduate Program in Cancer Biology

Center for Computational Science Fellowship

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. An Nkx2-5/Bmp2/Smad1 Negative Feedback Loop Controls Heart Progenitor Specification and Proliferation

2. Isl1 Identifies a Cardiac Progenitor Population that Proliferates Prior to Differentiation and Contributes a Majority of Cells to the Heart

3. The deployment of cell lineages that form the mammalian heart

4. Isl1 is a direct transcriptional target of Forkhead transcription factors in second heart field-derived mesoderm

5. Identification of regulatory elements in the Isl1 gene locus

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