Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures-Reference-Cited by-同舟云学术

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

Published:2021-11-26 Issue:48 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zafferani Martina¹^ORCID,Haddad Christina²^ORCID,Luo Le²^ORCID,Davila-Calderon Jesse²^ORCID,Chiu Liang-Yuan²^ORCID,Mugisha Christian Shema³^ORCID,Monaghan Adeline G.¹,Kennedy Andrew A.⁴^ORCID,Yesselman Joseph D.⁵,Gifford Robert J.⁶^ORCID,Tai Andrew W.⁴^ORCID,Kutluay Sebla B.³^ORCID,Li Mei-Ling⁷^ORCID,Brewer Gary⁷^ORCID,Tolbert Blanton S.²^ORCID,Hargrove Amanda E.¹^ORCID

Affiliation:

1. Chemistry Department, Duke University, 124 Science Drive, Durham, NC 27705, USA.

2. Department of Chemistry, Case Western Reserve University, Cleveland, OH 441106, USA.

3. Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.

4. Department of Internal Medicine and Department of Microbiology and Immunology, University of Michigan, 1150 W Medical Center Dr., Ann Arbor, MI 48109, USA.

5. Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.

6. MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Rd., Bearsden, Glasgow G61 1QH, UK.

7. Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.

Abstract

Small-molecule targeting of RNA stem loops in 5′-end of SARS-CoV-2 reveals novel RNA targets for viral inhibition.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference57 articles.

1. Comparing COVID-19 and the 1918–19 influenza pandemics in the United Kingdom

2. W. H. Organization WHO Coronavirus Disease (COVID-19) Dashboard. (2021).

3. Overview of lethal human coronaviruses

4. The emergence of SARS, MERS and novel SARS-2 coronaviruses in the 21st century

5. Origin and evolution of pathogenic coronaviruses

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40;British Journal of Pharmacology;2024-09-03

2. Recent advances in the molecular design and applications of viral RNA-targeting antiviral modalities;Drug Discovery Today;2024-08

3. Chemical Matter That Binds RNA;Methods and Principles in Medicinal Chemistry;2024-07-05

4. Outlook;Methods and Principles in Medicinal Chemistry;2024-07-05

5. Alpha- and betacoronavirus cis-acting RNA elements;Current Opinion in Microbiology;2024-06