The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria-Reference-Cited by-同舟云学术

The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria

Published:2019-09-06 Issue:9 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Wang Pengcheng¹^ORCID,Sachar Madhav¹^ORCID,Lu Jie¹,Shehu Amina I.¹^ORCID,Zhu Junjie¹,Chen Jing¹,Liu Ke¹,Anderson Karl E.²,Xie Wen¹,Gonzalez Frank J.³,Klaassen Curtis D.⁴,Ma Xiaochao¹^ORCID

Affiliation:

1. Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.

2. Porphyria Laboratory and Center, Departments of Preventive Medicine and Community Health, and Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.

3. Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

4. Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Abstract

The transporter ABCG2 determines phototoxicity and hepatotoxicity in erythropoietic protoporphyria.

Funder

National Institute of Allergy and Infectious Diseases

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference33 articles.

1. Porphyrin and heme metabolism and the porphyrias;Bonkovsky H. L.;Compr. Physiol.,2013

2. American Porphyria Foundation (APF 2014); http://www.porphyriafoundation.com/about-porphyria/types-of-porphyria/EPP.

3. Reduced ferrochelatase activity: A defect common to porphyria variegata and protoporphyria;Becker D. M.;Br. J. Haematol.,1977

4. Erythropoietic protoporphyria: Evidence that it is due to a variant ferrochelatase;Kramer S.;Int. J. Biochem.,1980

5. Clinical, biochemical, and genetic characterization of North American patients with erythropoietic protoporphyria and X-linked protoporphyria;Balwani M.;JAMA Dermatol.,2017

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