Influenza binds phosphorylated glycans from human lung-Reference-Cited by-同舟云学术

Influenza binds phosphorylated glycans from human lung

Published:2019-02 Issue:2 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Byrd-Leotis Lauren¹²^ORCID,Jia Nan²^ORCID,Dutta Sucharita²,Trost Jessica F.¹^ORCID,Gao Chao²^ORCID,Cummings Sandra F.²^ORCID,Braulke Thomas³^ORCID,Müller-Loennies Sven⁴^ORCID,Heimburg-Molinaro Jamie²,Steinhauer David A.¹^ORCID,Cummings Richard D.²^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.

2. Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.

3. Department of Biochemistry, Children’s Hospital, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.

4. Research Center Borstel (RCB), Leibniz Lung Center, Division Biophysics, Parkallee 22, D-23845 Borstel, Germany.

Abstract

A novel array of human lung glycans reveals influenza A virus binding to phosphorylated as well as sialylated N-glycans.

Funder

National Institute of General Medical Sciences

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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