Drag-induced directionality switching of kinesin-5 Cin8 revealed by cluster-motility analysis-Reference-Cited by-同舟云学术

Drag-induced directionality switching of kinesin-5 Cin8 revealed by cluster-motility analysis

Published:2021-02-05 Issue:6 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Pandey Himanshu¹^ORCID,Reithmann Emanuel²^ORCID,Goldstein-Levitin Alina¹^ORCID,Al-Bassam Jawdat³^ORCID,Frey Erwin²^ORCID,Gheber Larisa¹^ORCID

Affiliation:

1. Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 84105, Israel.

2. Arnold-Sommerfeld-Center for Theoretical Physics and Center for NanoScience, Ludwig-Maximilians-Universität München, Theresienstraße 37, D-80333 Munich, Germany.

3. Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616, USA.

Abstract

Directionality switching of the mitotic kinesin-5 Cin8 motor is caused by an asymmetric response of its active movement to drag.

Funder

National Science Foundation

National Institutes of Health

Deutsche Forschungsgemeinschaft

United States-Israel Binational Science Foundation

Israel Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject