A persulfidation-based mechanism controls aquaporin-8 conductance-Reference-Cited by-同舟云学术

A persulfidation-based mechanism controls aquaporin-8 conductance

Published:2018-05-04 Issue:5 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Bestetti Stefano¹^ORCID,Medraño-Fernandez Iria¹^ORCID,Galli Mauro¹,Ghitti Michela²^ORCID,Bienert Gerd P.³,Musco Giovanna²^ORCID,Orsi Andrea¹,Rubartelli Anna⁴^ORCID,Sitia Roberto¹

Affiliation:

1. Protein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.

2. Biomolecular Nuclear Magnetic Resonance (NMR) Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132 Milan, Italy.

3. Metalloid Transport Group, Leibniz Institute of Plant Genetics and Crop Plant Research, 06466 Gatersleben, Germany.

4. Cell Biology Unit, IRCCS Azienda Ospedaliera Universitaria (AOU) San Martino-IST, 16132 Genoa, Italy.

Abstract

A two-step posttranslational modification of AQP8 provides a mechanism regulating plasma membrane H 2 O 2 conductance.

Funder

Fondazione Telethon

Fondazione Cariplo

Ministero della Salute

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference54 articles.

1. Oxidative Stress

2. H 2 S: A Novel Gasotransmitter that Signals by Sulfhydration

3. Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

4. Tyrosine Kinase Signal Modulation: A Matter of H2O2 Membrane Permeability?

5. Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells

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