MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program-Reference-Cited by-同舟云学术

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program

Published:2021-01 Issue:1 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Wang Yi¹^ORCID,Zhang Lei¹^ORCID,Wu Guo-Rao¹,Zhou Qing¹,Yue Huihui¹,Rao Li-Zong¹²,Yuan Ting¹²,Mo Biwen²,Wang Fa-Xi¹,Chen Long-Min¹,Sun Fei¹,Song Jia¹,Xiong Fei¹,Zhang Shu¹,Yu Qilin¹,Yang Ping¹,Xu Yongjian¹,Zhao Jianping¹,Zhang Huilan¹^ORCID,Xiong Weining¹³^ORCID,Wang Cong-Yi¹^ORCID

Affiliation:

1. The Center for Biomedical Research, NHC Key Laboratory of Respiratory Diseases, Department of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, 1095 Jiefang Ave., Wuhan 430030, China.

2. Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guilin Medical University, 212 Renmin Road, Guilin 541000, China.

3. Department of Respiratory Medicine, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Lu, Shanghai 200011, China.

Abstract

Liposomes carrying MBD2 siRNA protect mice against BLM-induced lung injury and fibrosis by targeting macrophage M2 program.

Funder

Ministry of Science and Technology

National Natural Science Foundation of China

NHC Drug Discovery Program

the Department of Science and Technology of Hubei Province

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference55 articles.