An oligomeric semiconducting nanozyme with ultrafast electron transfers alleviates acute brain injury

Author:

Mu Xiaoyu1ORCID,Wang Junying12,He Hua3ORCID,Li Qifeng4,Yang Bing5ORCID,Wang Junhui6,Liu Haile2,Gao Yalong4,Ouyang Lufei2,Sun Si2,Ren Qinjuan2,Shi Xinjian3,Hao Wenting1,Fei Qiaoman5,Yang Jiang7ORCID,Li Lulin8ORCID,Vest Ryan910,Wyss-Coray Tony10ORCID,Luo Jian810ORCID,Zhang Xiao-Dong1ORCID

Affiliation:

1. Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.

2. Department of Physics and Tianjin Key Laboratory of Low Dimensional Materials Physics and Preparing Technology, School of Sciences, Tianjin University, Tianjin 300350, China.

3. State Key Laboratory of Heavy Oil Processing and Center for Bioengineering and Biotechnology, China University of Petroleum (East China), Qingdao 266580, China.

4. Department of Neurosurgery and Key Laboratory of Post-trauma Neuro-repair and Regeneration in Central Nervous System, Tianjin Medical University General Hospital, Tianjin 300052, China.

5. Department of Cellular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China.

6. State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

7. School of Medicine, Sun Yat-sen University, Guangzhou 510060, China.

8. Palo Alto Veterans Institute for Research, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA.

9. Department of Chemical Engineering, School of Engineering, Stanford University, Stanford, CA 94305, USA.

10. Department of Neurology and Neurological Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Abstract

An oligomeric nanozyme with ultrafast electron transfer can achieve high catalytic activity and alleviate acute brain injury.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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