Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria-Reference-Cited by-同舟云学术

Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria

Published:2018-05-04 Issue:5 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Sakatos Alexandra¹,Babunovic Gregory H.¹,Chase Michael R.¹^ORCID,Dills Alexander¹^ORCID,Leszyk John²,Rosebrock Tracy¹³^ORCID,Bryson Bryan¹,Fortune Sarah M.¹⁴

Affiliation:

1. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

2. Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 02129, USA.

3. Stonehill College, North Easton, MA 02357, USA.

4. The Ragon Institute of Massachusetts General Hospital, Harvard, and Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

A bacterial histone-like protein regulates the formation of privileged, drug-tolerant subpopulations of mycobacteria.

Funder

Burroughs Wellcome Foundation, NIAID

T32 AI

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference52 articles.

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