Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates-Reference-Cited by-同舟云学术

Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates

Author:

He Linling¹^ORCID,Lin Xiaohe¹,Wang Ying²³,Abraham Ciril²,Sou Cindy¹,Ngo Timothy¹,Zhang Yi²³,Wilson Ian A.¹⁴^ORCID,Zhu Jiang¹⁵^ORCID

Affiliation:

1. Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

2. Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA 19140, USA.

3. Department of Microbiology and Immunology, Temple University, Philadelphia, PA 19140, USA.

4. Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

5. Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Abstract

SARS-CoV-2 receptor binding domain and S2GΔHR2 spike elicited potent immune responses when displayed on protein nanoparticles.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference100 articles.

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