Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations-Reference-Cited by-同舟云学术

Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations

Published:2020-07-24 Issue:30 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Mandal Abhirup¹²^ORCID,Kumbhojkar Ninad¹²^ORCID,Reilly Charles²^ORCID,Dharamdasani Vimisha¹²,Ukidve Anvay¹²^ORCID,Ingber Donald E.¹²³^ORCID,Mitragotri Samir¹²^ORCID

Affiliation:

1. John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.

2. Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA 02115, USA.

3. Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA.

Abstract

A method is reported using ionic liquids for topical delivery of siRNA into skin for the treatment of psoriasis.

Funder

Leo Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

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2. Hierarchies of NF-κB target-gene regulation

3. NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis

4. A network-centric approach to drugging TNF-induced NF-κB signaling

5. Biologics in patients with skin diseases

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