Structural insights into the recognition of histone H3Q5 serotonylation by WDR5-Reference-Cited by-同舟云学术

Structural insights into the recognition of histone H3Q5 serotonylation by WDR5

Published:2021-06-18 Issue:25 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zhao Jie¹^ORCID,Chen Wanbiao¹²^ORCID,Pan Yi²^ORCID,Zhang Yinfeng²,Sun Huiying²,Wang Han²,Yang Fan²^ORCID,Liu Yu²^ORCID,Shen Nan²^ORCID,Zhang Xuan¹^ORCID,Mo Xi²^ORCID,Zang Jianye¹^ORCID

Affiliation:

1. Hefei National Laboratory for Physical Sciences at Microscale, the first affiliated hospital of USTC, MOE Key Laboratory for Membraneless Organelles and Cellular Dynamics, CAS Center for Excellence in Biomacromolecules, and School of Life Sciences, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China.

2. Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

Abstract

WDR5 specifically recognizes histone H3Q5ser to promote gene transcription and neuroblastoma cell proliferation.

Funder

North Carolina Central University

National Natural Science Foundation of China

University of Science and Technology of China

the Chinese Academy of Sciences Strategic Priority Research Program

The National Key Research and Development Program of China

the Science and Technology Commission of Shanghai Municipality

Publisher

American Association for the Advancement of Science (AAAS)

Subject