Delivery of RIPK4 small interfering RNA for bladder cancer therapy using natural halloysite nanotubes

Author:

Liu Jianye12ORCID,Zhang Yi3ORCID,Zeng Qinghai4ORCID,Zeng Hongliang5,Liu Xiaoming6,Wu Pei7,Xie Hongyi3,He Leye12,Long Zhi12,Lu Xiaoyong8,Xiao Mengqing9,Zhu Yuxing9,Bo Hao10,Cao Ke9ORCID

Affiliation:

1. Department of Urology, The Third Xiangya Hospital of Central South University, Changsha 410013, China.

2. Institute of Prostate Disease of Central South University, Changsha 410013, China.

3. School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China.

4. Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha 410013, China.

5. Hunan Key Laboratory of Pharmacodynamics and Safety Evaluation of New Drugs, Changsha 410331, China.

6. Department of Digestive, The Third Xiangya Hospital of Central South University, Changsha 410013, China.

7. Department of Operation Center, The Second Xiangya Hospital of Central South University, Changsha 410011, China.

8. Department of Urology, Hunan Aerospace Hospital, Changsha 410205, China.

9. Department of Onology, The Third Xiangya Hospital of Central South University, Changsha 410013, China.

10. Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha 410008, China.

Abstract

HNTs/siRIPK4 nanoparticles have been shown to be an effective treatment for bladder cancer.

Funder

National Natural Science Foundation of China

The Natural Science Foundation of Hunan Province

the New Xiangya Talent Projects of the Third Xiangya Hospital of Central South University

the Scientific Projects of Health and Family Planning Commision of Hunan Province

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

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4. RNA-Based Therapeutics: Current Progress and Future Prospects

5. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs;Matsumura Y.;Cancer Res.,1986

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