Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary-Reference-Cited by-同舟云学术

Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

Published:2020-05-22 Issue:21 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Chassot Anne-Amandine¹^ORCID,Le Rolle Morgane¹,Jolivet Geneviève²,Stevant Isabelle³^ORCID,Guigonis Jean-Marie⁴⁵,Da Silva Fabio¹⁶^ORCID,Nef Serge³^ORCID,Pailhoux Eric²^ORCID,Schedl Andreas¹^ORCID,Ghyselinck Norbert B.⁷^ORCID,Chaboissier Marie-Christine¹

Affiliation:

1. Université Côte d'Azur, CNRS, Inserm, iBV, Nice, France.

2. Université Paris-Saclay, INRAE, ENVA, BREED, 78350, Jouy-en-Josas, France.

3. Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.

4. Université Côte d’Azur, UMR E4320, CEA, F-06107 Nice, France.

5. Plateforme “Bernard Rossi”, Faculté de Médecine, Université Côte d’Azur, F-06107 Nice, France.

6. Division of Molecular Embryology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

7. Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Département de Génétique Fonctionnelle et Cancer, CNRS UMR7104, Inserm U1258, Université de Strasbourg (UNISTRA), 1 rue Laurent Fries, F-67404 Illkirch CEDEX, France.

Abstract

Retinoic acid synthesis is not essential for meiosis in fetal ovaries, challenging the dogma about the meiosis-inducing factors.

Funder

Agence Nationale de la Recherche

La Ligue Nationale Contre le Cancer

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference41 articles.

1. Mouse Primordial Germ Cells

2. Characterizing the bipotential mammalian gonad