Atoh7-independent specification of retinal ganglion cell identity

Author:

Brodie-Kommit Justin1ORCID,Clark Brian S.23ORCID,Shi Qing4,Shiau Fion2ORCID,Kim Dong Won5ORCID,Langel Jennifer6,Sheely Catherine1ORCID,Ruzycki Philip A2ORCID,Fries Michel78,Javed Awais78ORCID,Cayouette Michel78910ORCID,Schmidt Tiffany11ORCID,Badea Tudor1213ORCID,Glaser Tom14ORCID,Zhao Haiqing1,Singer Joshua4ORCID,Blackshaw Seth5151617ORCID,Hattar Samer6ORCID

Affiliation:

1. Department of Biology, Johns Hopkins University, Baltimore, MD, USA.

2. John F. Hardesty, MD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.

3. Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.

4. Department of Biology, University of Maryland, College Park, MD, USA.

5. Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

6. National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, MD, USA.

7. Cellular Neurobiology Research Unit, Institut de Recherches Cliniques de Montréal, Montréal, QC H2W 1R7, Canada.

8. Molecular Biology Programs, Université de Montréal, QC H3C 3J7, Canada.

9. Department of Anatomy and Cell Biology, McGill University, Montréal, QC H3A 0G4, Canada.

10. Department of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.

11. Department of Neurobiology, Northwestern University, Evanston, IL, USA.

12. National Eye Institute, National Institutes of Health, Bethesda, MD, USA.

13. Research and Development Institute, Transylvania University of Brasov, School of Medicine, Brasov, Romania.

14. Department of Cell Biology and Human Anatomy, University of California, Davis School of Medicine, Davis, CA, USA.

15. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

16. Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

17. Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA.

Abstract

Atoh7 promotes retinal ganglion survival and is not required for specification of most retinal ganglion cells.

Funder

National Institute of Mental Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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