Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate-Reference-Cited by-同舟云学术

Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate

Published:2019-06-07 Issue:6 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Candiracci Julie¹^ORCID,Migeot Valerie¹,Chionh Yok-Hian²^ORCID,Bauer Fanelie¹^ORCID,Brochier Thomas¹,Russell Brandon³^ORCID,Shiozaki Kazuhiro⁴⁵^ORCID,Dedon Peter²³^ORCID,Hermand Damien¹^ORCID

Affiliation:

1. URPHYM-GEMO, University of Namur, rue de Bruxelles, 61, Namur 5000, Belgium.

2. Singapore–MIT Alliance for Research and Technology Centre (SMART), Center for Life Sciences 05-06, 28 Medical Drive, 117456 Singapore.

3. Massachusetts Institute of Technology, 56-787B77 Massachusetts Avenue, Cambridge, MA 02139-4307, USA.

4. Division of Biological Science, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan.

5. Department of Microbiology and Molecular Genetics, University of California, Davis, CA 95616, USA.

Abstract

A feedback control is operating between TOR complex (TORC) signaling and tRNA modification by Elongator to enforce cell fate.

Funder

NIH Office of the Director

Fonds De La Recherche Scientifique - FNRS

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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