Granzyme B nanoreporter for early monitoring of tumor response to immunotherapy

Author:

Nguyen Anh1ORCID,Ramesh Anujan2,Kumar Sahana1ORCID,Nandi Dipika3,Brouillard Anthony1ORCID,Wells Alexandria3ORCID,Pobezinsky Leonid34ORCID,Osborne Barbara34ORCID,Kulkarni Ashish A.1234ORCID

Affiliation:

1. Department of Chemical Engineering, University of Massachusetts, Amherst, MA, USA.

2. Department of Biomedical Engineering, University of Massachusetts, Amherst, MA, USA.

3. Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA, USA.

4. Center for Bioactive Delivery, Institute for Applied Life Sciences, University of Massachusetts, Amherst, MA, USA.

Abstract

Granzyme B nanoreporter can distinguish between highly responsive and poorly responsive tumors.

Funder

National Institutes of Health

American Cancer Society

Cancer Research Institute

Melanoma Research Alliance

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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