Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver-Reference-Cited by-同舟云学术

Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver

Published:2021-04-23 Issue:17 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Mathur Bhoomika¹^ORCID,Shajahan Asif²^ORCID,Arif Waqar³^ORCID,Chen Qiushi²,Hand Nicholas J.⁴^ORCID,Abramowitz Lara K.⁵,Schoonjans Kristina⁶^ORCID,Rader Daniel J.⁴^ORCID,Kalsotra Auinash³^ORCID,Hanover John A.⁵^ORCID,Azadi Parastoo²,Anakk Sayeepriyadarshini¹⁷^ORCID

Affiliation:

1. Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

2. Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.

3. Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

4. Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

5. Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

6. École polytechnique fédérale de Lausanne, 1015 Lausanne, Switzerland.

7. Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Abstract

Loss of two hepatic nuclear receptors muddles the Golgi and the sugarcoat on proteins.

Funder

National Institutes of Health

Pakistan Academy of Sciences

American Cancer Society

National Institute of Health

National Institute of Diabetes and Digestive and Kidney Diseases

National Heart, Lung, and Blood Institute

National Institute on Alcohol Abuse and Alcoholism

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference59 articles.

1. M. E. Taylor K. Drickamer Introduction to Glycobiology (Oxford Univ. Press ed. 2 2006) p. 1733.

2. G. W. Hart C. M. West Nucleocytoplasmic Glycosylation in Essentials of Glycobiology A. Varki R. D. Cummings J. D. Esko H. H. Freeze P. Stanley C. R. Bertozzi G. W. Hart M. E. Etzler Eds. (Cold Spring Harbor Laboratory Press Cold Spring Harbor New York ed. 2 2009) Chapter 17. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1915/?report=classic.

3. Complex N-glycans: the story of the “yellow brick road”

4. N-linked glycosylation and homeostasis of the endoplasmic reticulum

5. Mechanisms and principles of N-linked protein glycosylation

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