A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques-Reference-Cited by-同舟云学术

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques

Published:2020-06-12 Issue:24 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

van Doremalen Neeltje¹^ORCID,Haddock Elaine¹,Feldmann Friederike²^ORCID,Meade-White Kimberly¹,Bushmaker Trenton¹,Fischer Robert J.¹^ORCID,Okumura Atsushi³^ORCID,Hanley Patrick W.²^ORCID,Saturday Greg²,Edwards Nick J.⁴^ORCID,Clark Madeleine H. A.⁴⁵,Lambe Teresa⁴^ORCID,Gilbert Sarah C.⁴^ORCID,Munster Vincent J.¹^ORCID

Affiliation:

1. Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.

2. Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.

3. Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.

4. The Jenner Institute, University of Oxford, Oxford, UK.

5. Transmission Biology Group, The Pirbright Institute, Pirbright, Woking, UK.

Abstract

Prime-only vaccination with ChAdOx1 MERS protects against HCoV-EMC/2012 in NHP and a variety of MERS-CoV strains in mice.

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference38 articles.

1. SARS and MERS: recent insights into emerging coronaviruses

2. WHO Middle East Respiratory Syndrome (2019); www.emro.who.int/health-topics/mers-cov/mers-outbreaks.html.

3. WHO (2020); https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200515-covid-19-sitrep-116.pdf?sfvrsn=8dd60956_2.

4. Environmental Contamination and Viral Shedding in MERS Patients During MERS-CoV Outbreak in South Korea

5. Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea, 2015: epidemiology, characteristics and public health implications

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