1. SUPA, School of Physics and Astronomy, University of St. Andrews, North Haugh, St. Andrews KY16 9SS, UK.
2. School of Medicine, University of St. Andrews, North Haugh, St. Andrews KY16 9FT, UK.
3. Biological Sciences, University of Southampton, University Road, Southampton SO17 1BJ, UK.
4. CRUK Edinburgh Centre, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK.