Organelle luminal dependence of (+)strand RNA virus replication reveals a hidden druggable target-Reference-Cited by-同舟云学术

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Organelle luminal dependence of (+)strand RNA virus replication reveals a hidden druggable target

Published:2018-01-05 Issue:1 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Nishikiori Masaki¹²³^ORCID,Ahlquist Paul¹²³⁴^ORCID

Affiliation:

1. Institute for Molecular Virology, University of Wisconsin-Madison, Madison, WI 53706, USA.

2. McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53706, USA.

3. Morgridge Institute for Research, Madison, WI 53715, USA.

4. Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, WI 53706, USA.

Abstract

New results link redox modulation, viroporin formation, and genome replication by (+)RNA viruses.

Funder

National Institutes of Health

Howard Hughes Medical Institute

Morgridge Institute for Research

Rowe Family Virology Venture Fund

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference52 articles.

1. Organelle-Like Membrane Compartmentalization of Positive-Strand RNA Virus Replication Factories

2. Cryo-electron tomography reveals novel features of a viral RNA replication compartment;Ertel K. J.;eLife,2017

3. Lipid tales of viral replication and transmission;Altan-Bonnet N.;Trends Cell Biol.,2017

4. Putative RNA capping activities encoded by brome mosaic virus: Methylation and covalent binding of guanylate by replicase protein 1a;Ahola T.;J. Virol.,1999

5. Brome mosaic virus 1a nucleoside triphosphatase/helicase domain plays crucial roles in recruiting RNA replication templates;Wang X.;J. Virol.,2005

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