Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver-Reference-Cited by-同舟云学术

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Published:2021-06-04 Issue:23 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Barthet Valentin J. A.¹²^ORCID,Brucoli Martina¹²^ORCID,Ladds Marcus J. G. W.¹^ORCID,Nössing Christoph¹²^ORCID,Kiourtis Christos¹²^ORCID,Baudot Alice D.¹,O’Prey James¹,Zunino Barbara¹,Müller Miryam¹^ORCID,May Stephanie¹^ORCID,Nixon Colin¹^ORCID,Long Jaclyn S.¹^ORCID,Bird Thomas G.¹³^ORCID,Ryan Kevin M.¹²^ORCID

Affiliation:

1. Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.

2. Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK.

3. MRC Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.

Abstract

Autophagy represses YAP/TAZ-dependent hepatocyte dedifferentiation into liver progenitor cells to prevent tumorigenesis.

Funder

Cancer Research UK

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference87 articles.

1. Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

2. Hepatocellular carcinoma

3. Liver fibrosis and repair: immune regulation of wound healing in a solid organ

4. Mammalian autophagy: core molecular machinery and signaling regulation

5. Autophagy and neurodegeneration

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Autophagy in aging-related diseases and cancer: Principles, regulatory mechanisms and therapeutic potential;Ageing Research Reviews;2024-09

2. Harnessing endocytic pH gradients for cascaded formation of intracellular condensates to inhibit autophagy: A pathway to cancer therapy;Nano Today;2024-08

3. Allicin regulates Sestrin2 ubiquitination to affect macrophage autophagy and senescence, thus inhibiting the growth of hepatoma cells;Tissue and Cell;2024-06

4. Investigating autophagy and intricate cellular mechanisms in hepatocellular carcinoma: Emphasis on cell death mechanism crosstalk;Cancer Letters;2024-04

5. Emerging Role of Autophagy in Governing Cellular Dormancy, Metabolic Functions, and Therapeutic Responses of Cancer Stem Cells;Cells;2024-03-04