Impact of parallel fiber to Purkinje cell long-term depression is unmasked in absence of inhibitory input-Reference-Cited by-同舟云学术

Impact of parallel fiber to Purkinje cell long-term depression is unmasked in absence of inhibitory input

Published:2018-10-05 Issue:10 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Boele Henk-Jan¹,Peter Saša¹^ORCID,Ten Brinke Michiel M.¹,Verdonschot Lucas¹,IJpelaar Anna C. H.¹,Rizopoulos Dimitris²,Gao Zhenyu¹,Koekkoek Sebastiaan K. E.¹^ORCID,De Zeeuw Chris I.¹³

Affiliation:

1. Department of Neuroscience, Erasmus MC, Rotterdam, Netherlands.

2. Department of Biostatistics, Erasmus MC, Rotterdam, Netherlands.

3. Netherlands Institute for Neuroscience, Royal Academy of Arts and Sciences (KNAW), Amsterdam, Netherlands.

Abstract

Simultaneous impairment of Purkinje cell inhibitory input and parallel fiber LTD severely affects cerebellar learning.

Funder

European Research Council

Netherlands Organisation for Health Research and Development

Erasmus Medisch Centrum

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference35 articles.

1. H. J. Boele M. M. Ten Brinke C. I. De Zeeuw Classical conditioning of timed motor responses: Neural coding in cerebellar cortex and cerebellar nuclei in The Neural Codes of the Cerebellum D. H. Heck Ed. (Academic Press 2015) pp. 53–96.

2. Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning;Freeman J. H.;Learn. Mem.,2011

3. Correspondence between climbing fibre input and motor output in eyeblink-related areas in cat cerebellar cortex;Hesslow G.;J. Physiol.,1994

4. Electrophysiological localization of eyeblink-related microzones in rabbit cerebellar cortex;Mostofi A.;J. Neurosci.,2010

5. Precise control of movement kinematics by optogenetic inhibition of Purkinje cell activity;Heiney S. A.;J. Neurosci.,2014

Cited by 56 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. What if…? Computational anatomy in the cerebellar microzone, the middle layer of the cerebellar network;2024-09-11

2. Discrimination training affects stimulus generalization in mice during Pavlovian eyeblink conditioning;Frontiers in Behavioral Neuroscience;2024-08-23

3. Different Numbers of Conjunctive Stimuli Induce LTP or LTD in Mouse Cerebellar Purkinje Cell;The Cerebellum;2024-08-03

4. Purkinje cell models: past, present and future;Frontiers in Computational Neuroscience;2024-07-10

5. Spiking network model of the cerebellum as a reinforcement learning machine;2024-06-28