High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA-Reference-Cited by-同舟云学术

High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA

Author:

O’Kane Patrick T.¹²^ORCID,Dudley Quentin M.¹³^ORCID,McMillan Aislinn K.¹²^ORCID,Jewett Michael C.¹³⁴^ORCID,Mrksich Milan¹²⁴

Affiliation:

1. Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.

2. Department of Chemistry, Northwestern University, Evanston, IL, USA.

3. Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.

4. Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.

Abstract

A chemical approach enables the rapid mapping of CoA metabolites in complex biological systems.

Funder

David and Lucile Packard Foundation

U.S. Department of Energy

Defense Threat Reduction Agency

Air Force Research Laboratory

Dreyfus Teacher-Scholar Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference47 articles.

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