PDLLA-Zn-nitrided Fe bioresorbable scaffold with 53-μm-thick metallic struts and tunable multistage biodegradation function-Reference-Cited by-同舟云学术

PDLLA-Zn-nitrided Fe bioresorbable scaffold with 53-μm-thick metallic struts and tunable multistage biodegradation function

Published:2021-06-04 Issue:23 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Shen Danni¹^ORCID,Qi Haiping²^ORCID,Lin Wenjiao²^ORCID,Zhang Wanqian²³,Bian Dong¹²^ORCID,Shi Xiaoli²,Qin Li²,Zhang Gui²,Fu Wenchao²,Dou Kefei⁴,Xu Bo⁴^ORCID,Yin Zhenyuan⁵^ORCID,Rao Jiancun⁶^ORCID,Alwi Mazeni⁷,Wang Shuhan⁸,Zheng Yufeng¹⁵^ORCID,Zhang Deyuan²^ORCID,Gao Runlin⁴^ORCID

Affiliation:

1. Beijing Advanced Innovation Center for Materials Genome Engineering and School of Materials Science and Engineering, Peking University, Beijing 100871, China.

2. National and Local Joint Engineering Laboratory of Interventional Medical Biotechnology and System, Lifetech Scientific (Shenzhen) Co. Ltd., Shenzhen 518110, China.

3. State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.

4. Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

5. BioMed-X Center, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.

6. AIM Lab, Maryland NanoCenter, University of Maryland, College Park, MD 20742, USA.

7. Paediatric Cardiology, Institut Jantung Negara (National Heart Institute), 145, Jalan Tun Razak, Kuala Lumpur 50400, Malaysia.

8. Shen Zhen Testing Center of Medical Devices, Shenzhen 518057, China.

Abstract

A novel PDLLA-Zn-FeN BRS biodegrades completely after ~2 years in rabbits and humans, with excellent biocompatibility.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Science, Technology and Innovation Commission of Shenzhen Municipality

Shenzhen Industrial and Information Technology Bureau

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference38 articles.

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