Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development-Reference-Cited by-同舟云学术

Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development

Published:2021-01-29 Issue:5 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zaksauskaite Ringaile¹^ORCID,Thomas Ruth C¹²^ORCID,van Eeden Freek¹²^ORCID,El-Khamisy Sherif F.¹³^ORCID

Affiliation:

1. Healthy Lifespan Institute, Sheffield Institute for Neuroscience, Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, UK.

2. Bateson Centre, Department of Biomedical Sciences, University of Sheffield, Sheffield S10 2TN, UK.

3. The Institute of Cancer Therapeutics, University of Bradford, Bradford BD7 1DP, UK.

Abstract

The repair of protein-linked chromosomal breaks requires distinct factors throughout the life span.

Funder

Wellcome

Biotechnology and Biological Sciences Research Council

Rosetrees Trust

Lister Institute of Preventive Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference66 articles.

1. The DNA Damage Response: Making It Safe to Play with Knives

2. DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms

3. Mutation of TDP1, encoding a topoisomerase I–dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

4. Conversion of Phosphoglycolate to Phosphate Termini on 3′ Overhangs of DNA Double Strand Breaks by the Human Tyrosyl-DNA Phosphodiesterase hTdp1

5. A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tyrosyl-DNA phosphodiesterase 2 (Tdp2) repairs DNA-protein crosslinks and protects against double strand breaks in vivo;Frontiers in Cell and Developmental Biology;2024-08-20

2. TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks;Cell Reports;2024-05

3. Consequences of directly- and indirectly-experienced heat stress in a mutagenic environment;2023-10-05

4. Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA–protein crosslinks in vivo;Open Biology;2023-10

5. Interplay between symmetric arginine dimethylation and ubiquitylation regulates TDP1 proteostasis for the repair of topoisomerase I-DNA adducts;Cell Reports;2022-06