Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy-Reference-Cited by-同舟云学术

Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy

Published:2020-05-22 Issue:21 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Wang Stephanie J.¹²^ORCID,Li Ran²^ORCID,Ng Thomas S. C.²^ORCID,Luthria Gaurav²³^ORCID,Oudin Madeleine J.⁴^ORCID,Prytyskach Mark²,Kohler Rainer H.²^ORCID,Weissleder Ralph²⁵⁶^ORCID,Lauffenburger Douglas A.¹^ORCID,Miller Miles A.²⁵^ORCID

Affiliation:

1. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

2. Center for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA, USA.

3. Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

4. Department of Biomedical Engineering, Tufts University, Medford, MA, USA.

5. Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

6. Department of Systems Biology, Harvard Medical School, Boston, MA, USA.

Abstract

Combining multicellular signaling profiles with in vivo imaging reveals how nanotherapy can block local resistance pathways.

Funder

National Science Foundation

National Institutes of Health

American Thyroid Association

Thyroid Cancer Survivors’ Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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