Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography-Reference-Cited by-同舟云学术

Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography

Published:2020-12-11 Issue:50 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zhang Xianjun¹^ORCID,Carter Stephen D.²^ORCID,Singla Jitin¹^ORCID,White Kate L.¹^ORCID,Butler Peter C.³,Stevens Raymond C.¹⁴^ORCID,Jensen Grant J.²⁵^ORCID

Affiliation:

1. Department of Biological Sciences, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA 90089, USA.

2. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

3. Larry Hillblom Islet Research Center, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

4. Department of Chemistry, Bridge Institute, USC Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA 90089, USA.

5. Howard Hughes Medical Institute (HHMI), California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

Multiple distinct tomograms of a single β cell enable investigation of the architecture of insulin vesicle neighborhoods.

Funder

National Institute of General Medical Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference46 articles.

1. Right Time, Right Place: Probing the Functions of Organelle Positioning

2. β-Cell Dysfunction in Subjects With Impaired Glucose Tolerance and Early Type 2 Diabetes