Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer-Reference-Cited by-同舟云学术

Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer

Published:2020-12-04 Issue:49 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Le Poul Yann¹^ORCID,Xin Yaqun¹^ORCID,Ling Liucong¹^ORCID,Mühling Bettina¹^ORCID,Jaenichen Rita¹,Hörl David²^ORCID,Bunk David²^ORCID,Harz Hartmann²^ORCID,Leonhardt Heinrich²^ORCID,Wang Yingfei³,Osipova Elena¹,Museridze Mariam¹,Dharmadhikari Deepak¹,Murphy Eamonn¹^ORCID,Rohs Remo³^ORCID,Preibisch Stephan⁴⁵^ORCID,Prud’homme Benjamin⁶^ORCID,Gompel Nicolas¹^ORCID

Affiliation:

1. Evolutionary Ecology, Ludwig-Maximilians Universität München, Fakultät für Biologie, Biozentrum, Grosshaderner Strasse 2, 82152 Planegg-Martinsried, Germany.

2. Human Biology and Bioimaging, Ludwig-Maximilians Universität München, Fakultät für Biologie, Biozentrum, Grosshaderner Strasse 2, 82152 Planegg-Martinsried, Germany.

3. Quantitative and Computational Biology, Departments of Biological Sciences, Chemistry, Physics and Astronomy, and Computer Science, University of Southern California, Los Angeles, CA 90089, USA.

4. Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13092 Berlin, Germany.

5. Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.

6. Aix-Marseille Université, CNRS, IBDM, Institut de Biologie du Développement de Marseille, Campus de Luminy Case 907, 13288 Marseille Cedex 9, France.

Abstract

A high density of regulatory information encodes a quantitative spatial pattern in a Drosophila transcriptional enhancer.

Funder

National Institutes of Health

FP7 Ideas: European Research Council

Deutsche Forschungsgemeinschaft

China Scholarship Council

Human Frontiers Science Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary