Discovery of direct-acting antiviral agents with a graphene-based fluorescent nanosensor

Author:

Park Se-Jin1ORCID,Kim Jungho12ORCID,Kang Seounghun1,Cha Hyung Jin13ORCID,Shin Hojeong1ORCID,Park Jisang4ORCID,Jang Yong-Suk45ORCID,Woo Jae-Sung36ORCID,Won Cheolhee2ORCID,Min Dal-Hee127ORCID

Affiliation:

1. Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.

2. Institute of Biotherapeutics Convergence Technology, Lemonex Inc., Seoul 08826, Republic of Korea.

3. Center for RNA Research, Institute for Basic Science (IBS), Seoul National University, Seoul 08826, Republic of Korea.

4. Department of Bioactive Material Sciences and Institute of Bioactive Materials, Jeonbuk National University, Jeonju 54896, Republic of Korea.

5. Department of Molecular Biology and the Institute for Molecular Biology and Genetics, Jeonbuk National University, Jeonju 54896, Republic of Korea.

6. Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea.

7. Department of Biological Sciences, Seoul National University, Seoul 08826, Republic of Korea.

Abstract

We report a novel high-throughput screening tool for drug discovery of direct-acting antiviral agents against RNA viruses.

Funder

National Research Foundation of Korea

Lemonex Inc.

Institute of Basic Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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