Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors-Reference-Cited by-同舟云学术

Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors

Published:2021-06-18 Issue:25 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Hörner Maximilian¹²^ORCID,Jerez-Longres Carolina¹²³^ORCID,Hudek Anna¹²^ORCID,Hook Sebastian¹,Yousefi O. Sascha¹²⁴^ORCID,Schamel Wolfgang W. A.¹²⁴^ORCID,Hörner Cindy⁵^ORCID,Zurbriggen Matias D.⁶,Ye Haifeng⁷^ORCID,Wagner Hanna J.¹²⁸^ORCID,Weber Wilfried¹²³^ORCID

Affiliation:

1. Faculty of Biology, University of Freiburg, Freiburg, Germany.

2. Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.

3. Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany.

4. Center of Chronic Immunodeficiency CCI, University Clinics and Medical Faculty, Freiburg, Germany.

5. Division of Veterinary Medicine, Paul-Ehrlich-Institut, Langen, Germany.

6. Institute of Synthetic Biology and CEPLAS, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

7. Synthetic Biology and Biomedical Engineering Laboratory, Biomedical Synthetic Biology Research Center, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.

8. Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.

Abstract

Engineered red light-responsive OptoAAV system allows spatiotemporally controlled gene transfer at single-cell resolution.

Funder

Canada’s Michael Smith Genome Sciences Centre

Deutsche Forschungsgemeinschaft

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference62 articles.

1. Single-cell biology: beyond the sum of its parts