Ultrafast pore-loop dynamics in a AAA+ machine point to a Brownian-ratchet mechanism for protein translocation
Author:
Affiliation:
1. Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 761001, Israel.
Abstract
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference46 articles.
1. AAA+ proteins: have engine, will work
2. AAA+superfamily ATPases: common structure-diverse function
3. The molecular principles governing the activity and functional diversity of AAA+ proteins
4. Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding
5. Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase
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