LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE-Reference-Cited by-同舟云学术

LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE

Published:2019-12-06 Issue:12 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Han Xiao¹²^ORCID,Huang Saihua¹²^ORCID,Xue Ping¹^ORCID,Fu Jinrong¹^ORCID,Liu Lijuan¹,Zhang Caiyan¹,Yang Lan¹,Xia Li¹,Sun Licheng¹,Huang Shau-Ku³⁴⁵⁶,Zhou Yufeng¹²^ORCID

Affiliation:

1. Children’s Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

2. NHC Key Laboratory of Neonatal Diseases, Fudan University, Shanghai, China.

3. National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli, Taiwan.

4. Johns Hopkins University School of Medicine, Baltimore, MD, USA.

5. Research Center of Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

6. Lou-Hu Hospital, Shen-Zhen University, Shen-Zhen, China.

Abstract

PTPRE-AS1 deficiency aggravates pulmonary inflammation but reduces colitis severity by modulating M2 macrophage activation.

Funder

National Natural Science Foundation of China

Kaohsiung Medical University

National Health Research Institutes

National key R&D program of China

Shanghai Committee of Science and Technology

Shanghai Pujiang Program

The International Joint laboratory Program of National Children’s Medical Center

Shanghai Municipal Planning Comission of Science and Research Fund

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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