DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood-Reference-Cited by-同舟云学术

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

Published:2018-01-05 Issue:1 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Tobi Elmar W.¹²^ORCID,Slieker Roderick C.¹,Luijk René¹³,Dekkers Koen F.¹,Stein Aryeh D.⁴^ORCID,Xu Kate M.³⁵^ORCID,Slagboom P. Eline¹^ORCID,van Zwet Erik W.³^ORCID,Lumey L. H.¹⁶,Heijmans Bastiaan T.¹^ORCID,

Affiliation:

1. Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, 2300 RC Leiden, Netherlands.

2. Division of Human Nutrition, Wageningen University and Research, 6708 WE Wageningen, Netherlands.

3. Medical Statistics, Department of Biomedical Data Sciences, Leiden University Medical Center, 2300 RC Leiden, Netherlands.

4. Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.

5. Faculty of Psychology and Educational Sciences, Welten Institute, Open University of the Netherlands, 6419 AT Heerlen, Netherlands.

6. Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.

Abstract

DNA methylation mediates the association of prenatal famine exposure with higher adult BMI and serum triglyceride levels.

Funder

National Institutes of Health

National Institute on Aging

European Research Council

Netherlands Organization for Scientific Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference75 articles.

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4. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

5. Glucocorticoid effects on the programming of AT1b angiotensin receptor gene methylation and expression in the rat;Bogdarina I.;PLOS ONE,2010

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